- Product Details
Keywords
- Orlistat
- 96829-58-2
- orlistat powder
Quick Details
- ProName: Orlistat
- CasNo: 96829-58-2
- Molecular Formula: C29H53NO5
- Appearance: White or almost white crystalline powd...
- Application: Active pharmaceutical ingredients to l...
- DeliveryTime: see order quantity
- PackAge: 5-25kg/drum or bag
- Port: ShangHai
- ProductionCapacity: 100 Kilogram/Day
- Purity: 98%
- Storage: 2~8℃
- LimitNum: 1 Kilogram
- Related Substances: Total Impurities:1.3%
Superiority
1.High quality with competitive price
2:medicine grade
3.High purity more than 99%
4.drug raw material to treat obesity
Details
CAS NO:96829-58-2
MF: C29H53NO5
Other name: TERAHYDROLIPSTATIN
Grade: medicine grade
Specification:
Appearance: white crystalline powder.
Solubility:very soluble in methanol and ethanol,freely soluble in chloroform,practically insoluble in water.
Melting point 42~44°C.
Specific rotation:-48~-51°
Identification HPLC:The retention time of principal peak should comply with its RS.
IR spectrum should comply with that of its RS.
Related substance.
Total impurities NMT 0.1%
Related Compound A: ND
Related Compound B: ND
Related Compound C: 0.019%
Related Compound D: ND
Related Compound E: 0.08%
Formylleucine ND
Orlistat open ring epimer ND
D-Leucine orlistat ND
Orlistat open ring epimer ND
Individual unidentified impurity 0.01%
Residual solvents
n-Heptane 820ppm
Isopropyl ether ND
Methanol ND
Tetrahydrofuran ND
Residual on Ignition 0.06%
Heavy metal not more than 20ppm
Assay 99.5%
Water 0.02%
Conclusion L Confirms with USP35
Usage:
Orlistat is a drug designed to treat obesity.
Its primary function is preventing the absorption of fats from the human diet by acting as a lipase inhibitor, thereby reducing caloric intake. It is intended for use in conjunction with a healthcare provider-supervised reduced-calorie diet.
Orlistat is the saturated derivative of lipstatin, a potent natural inhibitor of pancreatic lipases isolated from the bacterium Streptomyces toxytricini. However, due to its relative simplicity and stability, orlistat was chosen over lipstatin for development as an anti-obesity drug. The effectiveness of orlistat in promoting weight loss is definite, though modest.
Storage
Store at room temperature at 77 degrees F (25 degrees C) away from light and moisture. Brief storage between
59-86 degrees F (15-30 degrees C) is permitted.